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Friday, November 23, 2012

TRIPLE TEST (triple test)

PREGNANCY (PREGNANCY) TRIPLE TEST
The triple test (triple test) in maternal blood alphafetoprotein (AFP), free b-hCG and estriol (uE3) made by measuring a test. But it can be done between 15-22 weeks is usually done between 16-20 weeks. Such as the mother's arm, a small amount of blood taken for each assay, which is taken from the blood of the mother or the baby any harm or side effects. The sensitivity of the test, with the addition of a triple measurement of inhibin-A, which increased further quadruple test is done.

Hormone measurement results, mother's age, weight, smoking, and gestation variables such as whether it uses a computer program by entering the calculated risk. Objective chromosomal abnormalities Trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome) and neural tube defects (NTD) to determine the risks. Triple test and binary test, as distinct from the risk of neural tube defects can be determined through measurement of AFP.

As a result of this test for trisomy 21 risk 1/270 if greater than (for example 1/200), amniocentesis (mother's womb import process water) is recommended.

AFP test situations that could lead to the increase in value is considered high if the aminion fluid AFP. Detailed ultrasound examination of the baby's spinal cord (back) or abnormalities in the brain or whether it is an opening examined. In addition, ultrasound, it may cause an increase in AFP or other anomalies such as gastroschisis and omphalocele anomalies such as the baby's abdomen to the brain is not (anencephaly) as anomalies are investigated.

In the event of a high risk of trisomy 18 and trisomy 18 ultrasound examination abnormalities typical of the baby tries to be monitored. The most frequently seen abnormalities and cardiac anomalies of hands and feet. Trisomy 18 babies with very little portion (approximately 10%) be recognized on ultrasound abnormalities.

Overall, 70% of babies with Down syndrome can be obtained without the triple test. So the triple test can not detect approximately one in every three babies with Down's syndrome, the sensitivity is not very high.

Pregnant women over the age of 35 "generally" triple test done directly without the need for amniocentesis is recommended.

With increasing maternal age increases the risk of trisomy. If you have a history of an infant trisomic before a woman in subsequent pregnancies increases the risk of trisomy.

You always need to pay attention to the point: Double, triple and quadruple test for sure that the baby will never show any abnormality or disability than normal, increased or not increased the risk of not only refers to the anomaly. Anomaly show us whether the method is exactly the amniocentesis or CVS or cordocentesis is. (Amniocentesis: mother's womb the baby's bladder water intake process) every time ultrasound abnormalities such as trisomy 21 or 18 unnoticeable. In addition, the normal emergence of these tests does not mean that the baby is definitely anomaly. There is a certain amount of these tests margins of error.

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