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Friday, November 23, 2012

PREGNANCY (PREGNANCY) toxoplasma

TO INFECTION IN PREGNANCY toxoplasma

Toxoplasma, the parasite called toxoplasma gondii infection. Contamination of raw uncooked meat and cat feces defeated and cats have come into contact with the faeces of any goods ellenmesiyle is through the mouth. This disease has nothing to do directly with dogs. If infection to the baby through the placenta infection in pregnant women in this way people can also.
Cats are the main host of this parasite and the carrier.

Cat intestine parasite forms of the so-called divide and multiply, and oocyst sporozoit out with the feces are expelled into. These oocysts are highly resistant to the external environment. Transmitted to the external environment and from there everything human can pass through the mouth. Transmission of tissue cysts in undercooked or uncooked raw meats or unwashed fruits and vegetables of interference on the acquisition of oocysts is through the mouth. Oocysts were found in the soil in the hands or cat dung bulaşmasıyla noise through the mouth can be taken.

This infection after 5-18 day incubation period, normal healthy children or adults without a problem and does not require treatment often passed unnoticed. AIDS is a disease of the immune system in people with disfiguring and can cause problems for the baby during pregnancy. In fact, almost half of the people are infected with toxoplasma at some time in their lives, but most people do not have any symptoms. Generally, flu-like fever, fatigue, weakness, mild symptoms, such as muscle and joint pain resolve spontaneously.

On average 1-2 per 1000 pregnancies Sinde acute toxoplasma infection during pregnancy is passed. Infections, as well as other people who have passed on during pregnancy or just not noticeable most of the time, and the mother does not cause complaints.

What can harm the baby?
Infection rates as low as 15% in the first 3 months can pass to the baby. The passing rate of 30% in the second trimester the baby, the transition rate is 60% in the third trimester. However, the infection in the first trimester, the baby creates more serious problems. The infection causes less problems in the months ahead.
Does not create a risk for infection, pregnancy Pregnancy passed before they occur.

From the infection to the baby, in the womb of death, brain injury, hydrocephalus (water on the brain), cerebral calcification, vision problems (chorioretinitis), mental retardation, hearing problems, growth retardation, liver and spleen growth, pneumonia, myocarditis, can cause problems such as rash .

The classic triad of the disease, ie 1 triple damage hydrocephalus (water on the brain), 2 intracranial (brain) calcifications and 3 chorioretinitis (eye damage), respectively.

Some babies during pregnancy or immediately after birth, the baby passes the tests proved that the infection was observed in case of any damage or abnormality.

Not reveal an abnormality in infants at birth, although some long-term follow-up after years of seeing and hearing problems, neurological deficits were observed.

Diagnosis of maternal infection:
Interference with maternal antibodies against the parasite itself, or there are some methods for the determination. These mouse inoculation test, cell culture, and determination of parasite antigens, such as PCR and determination of parasite DNA tests. For the detection of maternal antibodies against interference Sabin-Fendman test, IFAT, IHA, EIA, ISAGA, such as ELISA tests are available.

IgM antibodies detected by these methods shows passed to new infection. IgG antibody was passed to the infection and acquired immune shows. However, these antibodies may not always very clear information. Sometimes it may remain positive for IgM antibody 1-2 years after infection. In this case, infection with toxoplasma IgG avidity test is obtainable about how much time passed before. Infection is high avidity test are passed at least 3 months before the shows. Low avidity test indicates infection are passed in the last 3 months.

IgM, IgG is negative, it's probably been a new infection. Both IgM and IgG positive test cases four fold increase in antibody titer was repeated after 3 weeks followed, this means that a new infection.

Both IgM and IgG antibody-negative persons who are not infected are by and noise so that they run the risks of being infected pregnant women in cat feces, raw and undercooked meats to stay clear.

The diagnosis of infection in the fetus:
Some of the tests, it is possible to determine whether or not the fetus. They are parasites in the blood of the fetus or amniotic fluid or detection of IgM antibodies, such as interference detection by PCR methods.

In addition, some of the infected fetuses with ultrasound anomalies described above can be observed.

Infection during pregnancy What should be done?
Toxoplasma infection is passed on during pregnancy would harm the baby said the exact risk as described above. This question describes risk family, spoken and family you want to terminate the pregnancy is terminated the pregnancy. Antibiotic therapy should be started immediately if the family does not want to terminate the pregnancy and after the birth of her child should continue to be given antibiotics. Prevent interference with the baby, but the baby will consist of antibiotic therapy decreases the severity of impacts. For this disease, spiramycin, pyrimethamine and sulfadiazine is used antibiotics.

What to do to Avoid:
Feed your cat at home during pregnancy must pay attention to some matters:
Pregnant women should not come into contact with the cat's feces. The cat feces and litter cleaning house persons who are not pregnant. Wash your hands with soap after touching a cat. This disease has nothing to do directly with dogs or cats, but cats can be infection in a dog has been in contact with the faeces.
Raw meat or undercooked meat, salami, sausage should not eat such foods.
Wash your hands thoroughly after contact with raw meat with bare hands.
Thoroughly wash raw meat cut blades.
You should eat plenty of fruits and vegetables by washing with water or wash your hands after handling them.
Be removed and canned foods fed the cats out.
Garden and should not come into contact with the soil bare hands, hands should be washed thoroughly even if contact.
Hands should be applied on the mouth and eyes.
In order to avoid flies or insects to carry oocyst kulllanın window filters.  

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