Prolactin (PRL, milk hormone) EXCESS
(Hyperprolactinemia)
Prolactin (PRL, milk hormone) What?
Prolactin is the hormone secreted by the pituitary gland located in the
central area of the brain structure of the peptide hormone. In short, be written in the form of PRL. Also called the pituitary gland pituitary gland. The secretion of the hormone prolactin from the pituitary gland is controlled by the hypothalamus area of the brain again. Reduces dopamine secreted by the hypothalamus that inhibits the secretion of the hormone prolactin. TRH is the hormone secreted by the hypothalamus to increase the secretion of prolactin effect. (TRH: thyrotropin-releasing hormone)
Prolactin (PRL) hormone should be the normal number of values?
Although changes in menstrual cycles in women with hormone prolactin as the value of yaklaşıl 13-15 mg / L is around. Ie the middle of the menstrual period ovulation (ovulation) days may be close to the days a little more height. As a result, women of reproductive age is usually 20 mg / L (ng / mL) values above are considered abnormally high.
Months of pregnancy progresses, the level of prolactin increases, and reaches values above the normal range.
Males usually 6-10 mg / L has values ranging from.
Prolactin (PRL) hormone effects?
The effects of a wide variety of male and female bodies of the hormone prolactin, have a duty. Some of them are still in the research stage effects net undetected. The sharpest and best-known effects include:
- Providing women with breast milk production
- Sexual desire and desire are related tasks.
- Has implications stages of sperm production in males
Prolactin (PRL, milk hormone) height symptoms:
Prolactin elevation "hyperprolactinemia," he called.
- Anovulation and menstrual irregularity: the height of the hormone prolactin lack of ovulation or ovulation disorders, accordingly units (mens) disorders, can cause symptoms such as thinning volumes. Sometimes it can cause long-lasting not to see ads for months.
- Pregnant or postpartum, non-breastfeeding women, breast milk (liquid) come what may. However galactorrhea is called. Breast tenderness and pain may occur.
- Prolactin elevation can cause female sexual reluctance.
- Vagina dryness and pain during sexual intercourse due to
- Hot flushes (menopause-like symptoms)
- Düşüklüğe caused by the hormones estrogen and testosterone for osteoporosis (osteoporosis) may result.
- Göğüsşerde height growth hormone prolactin in men (gynecomastia),
decreased sex drive, can cause symptoms such as sertleşememe.
- Both sexes due to the height of the hormone prolactin, this adenoma
adenoma of the pituitary gland is a growing optic nerve (the nerve to
the eye) to the compression of vision problems may occur as a result.
Diagnosis (diagnosis):
With the value of the hormone prolactin levels with a blood test or a decrease in prolactin elevation can be determined.
At a later stage some of the other hormone tests to investigate the
cause of it, or brain imaging (MRI, CT, X-ray etc ...) may be required.
The brain, the pituitary gland adenoma prolactin value is too high (100
mg / L to high) investigated, in order to show the pituitary adenoma
MRI, computed tomography (CT, CT) is superior to.
Thyroid hormone levels (primary hypothyroidism) can cause TRH hormone prolactin elevation height as to why. For this reason, thyroid (goiter) hormones evaluated.
If the drugs that can cause prolactin elevation of the patient,
psychiatric If you have a problem, they are also considered among the
possible causes.
Prolactin (PRL) yükseliğinde reasons:
* Prolactin is the hormone that causes an increase in the physiological reasons:
- Pregnancy
- Breastfeeding
- Sexual intercourse, touching nipples
- Exercise
- Stress
- Sleep
* Prolactin is the hormone that causes an increase in drugs:
- Dopamine receptor antagonists and inhibitors of dopamine synthesis
- Antipsychotic drugs
- Opiate drugs
- Atikonvülzan drugs (epilepsy drugs)
- Some antihypertensive drugs
- Some antihistamine drugs
- Estrogen-containing medicines (birth control pills containing
estrogen, low milktarda usually does not cause prolactin elevation.)
* An increase in the hormone prolactin, which cause diseases:
- Conditions that cause damage to the hypothalamus pituitary axis: tumor, trauma, such as infiltration of reasons. Hipotalustan pituitary prolactin rises to obstruct ihhibisyonu with the dopamine effect.
- Of the pituitary adenomas: prolactinomas (adenomas laktotrop, macroadenoma, microadenomas)
- Some systemic and chronic diseases
- Acromegaly
- Cushing's disease
- Hypothyrodism (low thyroid hormone)
- Chronic renal yetmezliğği
- Bronchogenic carcinoma
- Sarcoidosis
- Severe chest wall trauma: Emzirmedeki neural mechanism that causes a similar increase in the hormone prolactin.
Idiopathic hyperprolactinemia:
Mild prolactin (milk hormone, prolactin), the majority of patients with
high levels can cause despite all the research, this condition is
called idiopathic hyperprolactinemia. Hiperprolaktinomada Idiopathic prolactin value is generally 20 -100 ng / mL (mcg / L) range.
Prolactin (milk hormone) yükekliği pregnancy (pregnancy) obstacle sturdy?
Prolactin elevation ovulation (ovulation), blocked to prevent pregnancy. In this case, seviyeseni prolactin-lowering drug or surgical treatment is rarely necessary. If necessary, treatment, ovulation, regulatory drug treatments are added.
Prolactin is not to high, spawning denilemez, will spawn an irregular
way, though, and in this way often may result in pregnancy. Ovulation amenorrhoea or menstrual irregularities due to irregularities, such as sparsity are also common symptoms.
To IVF in patients with prolactin (milk hormone) levels are reduced to
normal levels as a result of the collection of eggs and egg IVF
enhancement treatments can be applied. Elevation of prolactin in vitro fertilization
is not an obstacle for the application of in vitro fertilization but
before application of the treatment of hyperprolactinemia may be
required.
Prolactin (PRL, milk hormone) treatment of height:
Prolactin hormone (milk hormone) in height is usually called dopamine
agonist drug therapies (brorokriptin, cabergoline) is applied. However, the cause of the height of prolactin are necessary for the treatment.
If you have a large adenoma in the pituitary gland that causes an
increase in prolactin is sometimes applied to this type of surgery. These situations should be evaluated by a specialist in neurosurgery.
Each type of blood at regular intervals during the treatment period is
followed by looking at the level of the hormone prolactin.
Prolactin hormone (milk hormone, prolactin) reduces food, foods, plants, herbs, cures:
Prolactin elevation (or loss) is strictly to be followed by rigor and doctors who specialize in this condition.
No plant, weed, cure, food, food, drinks, etc. will not provide benefit
to patients in this regard as a waste of time and bring some
significant losses.
Prolactin (PRL, MILK hormone) Impairment:
Dopamine, antiparkinson drugs, pathologies related to the pituitary
gland (Sheehan's syndrome), pituitary tumors, head trauma, certain
infections, infiltrative diseases, for reasons such as reduction in the
level of the hormone prolactin may occur. Avoid the main symptom of breast milk in women after giving birth. Prolactin elevation is not so frequent.
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